This data comes from a clinical trial investigating whether the drug cholostyramine lowered blood cholesterol levels. The men were supposed to take six packets of cholostyramine per day, but many actually took much less.
Compliance: Percentage of the intended dose actually taken (as measured by pill counts)Improvement: Decrease in cholesterol from the beginning to the end of the trial (mg/dL)Efron B and Feldman D. (1991). Compliance as an Explanatory Variable in Clinical Trials. Journal of the American Statistical Association, 86:9-17.