Two groups of female rats were exposed to the carcinogen DMBA. The two groups differed with respect to a pretreatment regime (unfortunately, no further detail was provided in the original paper). The purpose of the study was to determine whether the course of the disease, as measured by the time until death from vaginal cancer, differed by group.
Group: Experimental group (0, 1)Time: Time on study (days)Death: Death indicator (1=death, 0=censored)I obtained the data from
Kalbfleisch JD and Prentice RL (2002). The Statistical Analysis of Failure Time Data (2nd edition), Wiley.
The original source is
Pike MC (1966). A method of analysis of a certain class of experiments in carcinogenesis. Biometrics, 22:142-161.